Indian Scientists developed Insulin Pill for diabetics

Indian Scientists developed insulin pill for diabetics published in American Chemical Society journal biomacromolecules, Washington on 20 December 2013.

Created On: Dec 21, 2013 16:54 IST

The Indian Scientists, National Institute of Pharmaceutical Education and Research (NIPER) developed insulin pill for diabetics in third week of December 2013.

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The Scientists developed a long-sought insulin pill that could spare millions of diabetics and soughed a way the delivery of insulin therapy from a jab to a pill.

The experiments with rats, the pill lowered blood glucose levels almost as much as injected insulin and the effects of the pill lasted longer than injected insulin.

The body’s digestive enzymes in the body are so good at breaking down food also break down insulin before it can get to work. In addition, insulin does not get easily absorbed through the gut into bloodstream.

To solve these problem researchers from National Institute of Pharmaceutical Education and Research (NIPER) in Punjab combined two approaches to shield insulin from the digestive enzymes and then get it into the blood.

The team of researchers Ashish Kumar Agrawal, Harshad Harde, Kaushik Thanki and Sanyog Jain, packaged insulin in tiny sacs made of lipids or fats called liposome.Then wrapped the liposomes in layers of protective molecules called polyelectrolytes.
To get absorbed and to transport the layersome across the intestinal wall into the blood stream they attached folic acid and a kind of vitamin B.

This was published in American Chemical Society journal biomacromolecules, Washington.

About Diabetics:
Diabetics also called as diabetic mellitus, describes a group of metabolic diseases in which the person has high blood glucose (blood sugar) either because insulin production is inadequate or because the body's cells do not respond properly to insulin or both.

There are three types of diabetics that is Type1 diabetics, Type2 diabetics and Gestational Diabetes

An estimated 347 million people globally are living with diabetes. Diabetics must test their blood sugar several times and need insulin jabs for the rest of their lives in order to maintain adequate levels of the hormone.

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