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Scientists created the world's first ultra-high resolution 3D model of a HUMAN BRAIN

Scientists in the Month of June 2013 have created the world's first high-definition 3D model of a complete human brain which is named by Big Brain.

Jun 30, 2013 11:49 IST
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HUMAN BRAINScientists in the Month of June 2013 have created the world's first high-definition 3D model of a complete human brain which is named by Big Brain.

The 3D model of a HUMAN BRAIN was prepared by mounting thin sliced sections of the whole-brain on slides. The stained sections were then scanned and reconstituted by supercomputers into a 3D model of an entire brain.

The Scientist used a tool called a microtome by which they have sliced the postmoterm brain of a 65 year old woman preserved in paraffin wax into about 7400 sections each 20 microns thick and used it to create the most detailed map yet of a human brain.

It has taken several years for supercomputers in Germany and Canada to reconstruct images of the slide-mounted thin sections into a 3D volume image of the brain, taking into account tears and wrinkles in individual slices of thin and thus fragile tissue.

During the formation of Brain around 80 billions neurons were captured. It is conceived that Scientists from Canada and Germany spent 1000 years collecting the data and the total brain reconstruction has taken 10 years to complete.

Some Facts About Big Brain

• The BigBrain is 250000 times more detailed than a regular brain scan.
• The Big Brain was created using 7400 individual slices from the brain of a deceased 65-year-old woman.
• Each individual slice is half the width of a human hair.
• The brain can be seen in microscopic detail at a spatial resolution of 20 microns.
• The Brain shows the anatomy of a brain in microscopic detail for the first time ever - at a spatial resolution of 20 microns which is smaller than the size of one fine strand of hair and 250000 times more detailed than current MRI brain scans.
• The Big Brain presents the analytic details of organization of cerebral neurons at an unprecedented resolution of 20 micrometers, about 50 times higher than the resolution of previous atlases of the brain constructed from whole brain scans.

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