Global Road Safety Week 2019; Sunscreen can affect bloodstream - Current Affairs
WHO report highlights that road accidents are the major concern for death among people age group between 5 to 29 years.
Story 1: Global Road Safety Week 2019 celebrated
Fifth global road safety week is being celebrated between May 06 to 12, 2019. Theme for this year is -“Leadership for road safety”. United Nation believes that global goals can be achieved only if precious life is safe. To make it sure, UN has launched action through the ongoing campaign: Save Lives #SpeakUp.
World Health Organisation (WHO) has released a report during road safety week. This report highlights that road accidents are the major concern for death among people age group between 5 to 29 years. Report also indicates that 1.35 million people die each year due to road accidents worldwide.
About #SpeakUp Campaign
- The #SpeakUp campaign runs on the philosophy of the Decade of Action for Road Safety 2011-2020.
- Many countries started adopting the first global Decade of Action on May 10, 2011.
- Governments committed to taking new steps to save lives on their roads from New Zealand to Mexico and the Russian Federation to South Africa.
- This project seeks to mitigate number of road accident deaths and injuries as reports indicating that 1.9 million people will be affected by 2020.
- The Global Plan for the Decade of Action outlines steps towards improving road safety within 5 pillars of activity: road safety management, safer roads and mobility, safer vehicles, safer road users, and post-crash response.
Story 2: Sunscreen can affect bloodstream: Study
A report published in Journal of the American Medical Association (JAMA) explained usage affects of sunscreen in human bloodstream. In a randomized clinical trial done by researchers, involving healthy volunteers, usage of sunscreen resulted in plasma concentration that surpasses the limit established by US food and drug association (FDA). Clinical research also found some adverse affects on human hormones.
As per the report bloodstream levels found increased with chemicals used in sunscreens, lotions and sprays. To get best results, tests were conducted on healthy volunteers for four days as directed on the product label. Despite report, experts suggesting not to stop using sunscreen because sun’s harmful rays can be prevent only with available products.
- Report highlights that chemicals including in manufacturing of sunscreens are – avobenzone, octocrylene and oxybenzone to prevent harmful sun rays. Companies claim that these chemicals absorb radiation and switch it into a tiny amount of heat.
- After applying sunscreens for four days, regular tests were conducted on volunteers through blood samples.
- Researchers found levels of avobenzone, octocrylene, oxybenzone and ecamsule increased in the bloodstream. It means all these chemicals goes into the skin and meet with the bloodstream.
- Report published in JAMA said that the systemic absorption of sunscreen ingredients supports the need for further studies to determine the clinical significance of these findings. These results do not indicate that individuals should refrain from the use of sunscreen.
Affects on Human Body
Avobenzone: All 4 sunscreen products resulted in avobenzone exposures, with plasma concentrations exceeding 0.5 ng/mL .
Oxybenzone: Three products with oxybenzone resulted in oxybenzone exposure, with plasma concentrations exceeding 20 ng/mL on day 7.
Octocrylene: All 4 products resulted in octocrylene exposures, with plasma concentrations exceeding 0.5 ng/mL, starting from day 1 and lasting through day 7.
Ecamsule: The cream was the only product containing ecamsule. Five of 6 participants had an ecamsule plasma concentration exceeding 0.5 ng/mL on day 1.
In this study on healthy volunteers, application commercially available sunscreens under maximal use conditions resulted in plasma concentrations that exceeded the threshold established by the FDA for potentially waiving some nonclinical toxicology studies for sunscreens. The systemic absorption of sunscreen ingredients supports the need for further studies to determine the clinical significance of these findings. These results do not indicate that individuals should refrain from the use of sunscreen.
Indian drug regulatory authority
Central Drugs Standard Control Organization (CDSCO) is the national regulatory body for Indian pharmaceuticals. However, cosmetic products in India are regulated under the Drugs and Cosmetics Act 1940 and Rules 1945. To sell cosmetic products in India registration under Central Drugs Standard Control Organization (CDSCO) is mandatory.