One-in-Three Alzheimer's cases are preventable: Cambridge University Research

Jul 14, 2014 15:33 IST

A research report from the University of Cambridge said that one in the three cases of Alzheimer’s disease worldwide is preventable. The research report is titled Potential for primary prevention of Alzheimer's disease: an analysis of population-based data.

The study was published in the August 2014 edition of the journal Lancet Neurology. The study was led by Professor Caroline Brayne, from the Cambridge Institute of Public Health at the University of Cambridge.

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The study was funded by National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care for Cambridgeshire and Peterborough.

Main Findings of the Study
• Lack of exercise, smoking, depression and poor education are the main risk factors of the disease, however, age was still the biggest risk factor
• The highest estimated Population-Attributable Risk (PAR) worldwide was for low educational attainment
• The combined PAR for the seven risk factors was 49.4 percent which equates to 16.8 million attributable cases of 33.9 million cases worldwide
• The seven risk factors identified in the study are: Physical inactivity; Depression; Smoking; Low educational attainment; Diabetes; Mid-life hypertension and Mid-life obesity
• These seven risk factors are responsible for one-third or 30 percent of the Alzheimer cases worldwide
• The number of the affected people can be reduced by reducing these factors
• Reducing each factor by 10 percent will reduce the prevalence of Alzheimer by about nine million or 8.3 percent by 2050
• It also suggested that more than 106 million people of the world will be living with the disease by 2050. The predicted number is three times more that the number affected (34 million) in 2010
• Physical inactivity was the main cause for the largest proportion of cases of Alzheimer's in the US, UK and the rest of Europe

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