Scientists from Cedars-Sinai Medicla Centre, Los Angeles, for the first time developed a blood test to determine if a person is suffering from Irritable Bowel Syndrome (IBS), or another serious condition such as Inflammatory Bowel Disease (IBD).
Researchers conclusively identified a test for antibodies that form against a particular protein, vinculin, found in the guts of patients.
The study and results of the research work were presented on 11 October 2013 at the American College of Gastroenterology's 78th Annual Scientific Meeting in San Diego, California.
In the study, 221 patients were evaluated; some had a diagnosis of IBS, some were diagnosed with IBD and some were healthy, with no symptoms. Anti-vinculin antibodies were significantly elevated in IBS patients as compared to those with IBD or those who were healthy.
Until this study, there had been no accurate biomarkers identified specifically for IBS. The new blood test has the potential to distinguish IBS from IBD and reduce the need for unnecessary testing, expense and years of suffering.
About Irritable Bowel Syndrome (IBS)
Irritable Bowel Syndrome is a gastrointestinal disorder characterised by diarrhea, bloating and abdominal pain. However, millions of patients are never diagnosed correctly.
A simple blood test at the first sign of symptoms means patients who have IBS could get effective treatment sooner.
Food poisoning has been identified as a significant risk factor for developing this disorder which is characterized by a cluster of symptoms including diarrhea, bloating and abdominal pain.
When: October 2013
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