Scientists found in Hytholamus the Mechanism Responsible for Ageing
The US team of scientists found the mechanism in the hypothalamus responsible for the ageing process.
The US team of scientists found the mechanism in the hypothalamus- which is located deep inside the brain- and showed that it is responsible for the ageing process. Scientists carried out a series of experiments to find that they could extend the lives of mice by a fifth, without the problems such as animals suffering from muscle weakness, bone loss or memory problems associated with old age.
Scientists discovered that a chemical called NF-kB became more active in the hypothalamus of mice as they reached old age. When they blocked NF-kB, mice lived up to 1100 days, compared with 600 to 1000 days in normal condition. But all the mice died within 900 days, when NF-kB was given to them in abundance.
Further experiment showed that NF-kB reduced levels of a hormone called GnRH, which plays a key role in fertility and the development of sperm and eggs. When the mice were given daily dose of GnRH, it resulted into fresh neurons growing in their brains.