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Researchers identified that Brain has weak spot for schizophrenia and Alzheimer’s disease

The team of British researchers led by Gwenaelle Douaud of Oxford University identified that brain has weak spot for schizophrenia and Alzheimer’s disease.

Dec 1, 2014 13:01 IST
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The team of British researchers led by Gwenaelle Douaud of Oxford University identified that brain has weak spot for schizophrenia and Alzheimer’s disease. The findings were published in Journal Proceedings of the National Academy of Sciences (PANS) on 24 November 2014.

The Study
Researchers from the University of Oxford used Magnetic Resonance Imaging (MRI) scans to observe brain structure in 484 healthy people between ages 8 and 85.

The scans revealed a sort-of brain network within grey matter that is the last to develop and also the first to show signs of age-related decline.

This brain network of nerve cells or grey matter co-ordinate high order information coming from the different senses such as sight and sound.

This complex region shows heightened vulnerability to unhealthy developmental and aging processes as shown by schizophrenia and Alzheimer’s disease even though these two diseases have different origins and appear at very different times of life.

When team compared their study scans to those done on Alzheimer's and schizophrenia patients, they found significant similarities between the three. This would suggest certain areas of the brain play a role in the emergence of these diseases.

This large-scale and detailed study provides an important link between development, aging, and disease processes in the brain.

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