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Principles of Inheritance and Variations (Part-2)

Failure of segregation of chromatids during cell division cycle results in the gain or loss of a chromosome(s), called aneuploidy. For example, Down’s syndrome results in the gain of extra copy of chromosome 21. Similarly, Turner’s syndrome results due to loss of an X chromosome in human females.

Created On: Jan 14, 2013 17:00 IST
Modified On: May 30, 2014 14:29 IST
Principles of Inheritance and Variations (Part-2)
Principles of Inheritance and Variations (Part-2)

What is sex determination? What do mean by the tem Chromosomal disorders? To get more details about the topic sex determination please go through the video.

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During spermatogenesis among males, two types of gametes are produced. 50 per cent of the total sperm produced carry the X-chromosome and the rest 50 per cent has Y-chromosome besides the autosomes. Females, however, produce only one type of ovum with an X-chromosome. There is an equal probability of fertilisation of the ovum with the sperm carrying either X or Y chromosome. In case the ovum fertilises with a sperm carrying X-chromosome the zygote develops into a female (XX) and the fertilisation of ovum with Y-chromosome carrying sperm results into a male offspring.
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