Which is the Most Rare Blood Group in the World? And It’s Not O-Negative!

Most Rare Blood Group: The rarest blood group is Rh-null, with only a few cases reported worldwide. It lacks all Rh antigens, making it compatible with anyone but difficult to find compatible blood for individuals with this type. This rarity poses significant challenges for transfusions and medical care.

Apr 16, 2025, 19:22 IST
Which is the Most Rare Blood Type in the World? Check Here
Which is the Most Rare Blood Type in the World? Check Here

Rarest Blood Type in the World: According to Stanford Blood Centre, there are a total of 8 types of blood groups, which are categorised based on the presence or absence of certain antigens on the surface of red blood cells. These blood groups include A, B, AB, and O, each with positive or negative Rh factors.

In many movies and cases, it is primarily shown that the O-Negative Blood group is the most rare blood group in the world.

However, in reality, AB negative is the rarest blood type, with only about 1% of the population having it. This makes it in high demand for blood donations.

But wait! There is another blood type that is even rarer than AB negative, but for that, you have to read the complete article to know which blood type holds that title. Shall we start?

Which is the Rarest Blood Group?

Source: Research Gate

Do you know how blood groups are classified as rare or not? According to the American Red Cross, the most rare blood type is one that occurs in fewer than one in every 1,000 people.

And do you know which is the rarest blood group after AB negative? It's Rh-null. Researchers estimate that only one in every six million people has Rhnull blood. Rh-null blood is sometimes referred to as the "golden blood type" due to its rarity.

So, if you have the Rh-null blood type, you should exercise caution when driving or doing anything risky because having a rare blood type like this makes it difficult (not impossible) to receive a blood transfusion or organ transplant.

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Kriti Barua
Kriti Barua

Executive Content Writer

Kriti Barua is a professional content writer who has four years of experience in creating engaging and informative articles for various industries. She started her career as a creative writer intern at Wordloom Ventures and quickly developed a passion for crafting compelling narratives that resonate with readers.

Currently working as a content writer for the GK section of Jagran New Media, she continues to hone her skills in writing and strives to deliver high-quality content that educates and entertains readers.
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