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Which is the largest gland in the human body?

Last Updated: Aug 11, 2025, 16:56 IST

The liver is the largest gland and internal organ in the human body, weighing about three pounds and located under the ribs on the right side. It functions as both an exocrine gland by producing bile for digestion and an endocrine gland by releasing vital proteins and hormones, while also detoxifying blood and supporting metabolism.

Which is the largest gland in the human body?
Which is the largest gland in the human body?

In the human body, all the parts of human play an important role in living a good and healthy life. But all organs have their own and different role, and each organ is categorised for its role. So, do you often realise which is the largest gland in the human body?

Among all the organs in our body, the liver holds a special place—not only because of its size but also due to the many critical roles it plays. The liver is located on the right side of the abdomen, just beneath the ribs. 

The liver is a reddish-brown, spongy organ roughly the size of a football. In an average adult, it weighs about three pounds, making it the largest internal organ and the biggest gland in the human body.

In this article, let’s explore in detail the largest gland in the human body, which is none of the Kidney only.

Which is the largest gland in the human body?

The liver is the largest gland in the human body. Liver is doing its functions as both an exocrine gland by producing bile for digestion, and it also acts as an endocrine gland by releasing important proteins and hormones into the blood. The liver also helps in detoxifying harmful substances by aiding metabolism and maintaining body balance.

Why is the Liver Called a Gland?

The liver is often described as both an organ and a gland. The liver, which is an internal part of the human body, is also known as a gland because it produces important substances that the body needs to function properly. Specifically, it acts as an exocrine gland by secreting bile, which is a fluid that is essential for digesting fats, directly into the intestines. At the same time, it also has to perform the endocrine functions, which help in filtering the blood.

Source: hopkinsmedicine

What are the functions of the  Liver?

The liver is considered a powerhouse of metabolic activity in human body, which carries out hundreds of tasks every day to keep us healthy. Some of its most vital functions include:

Function

Description

Toxin Removal

It helps in filtering harmful substances from the blood

Breakdown of Old Blood Cells

It recycles the components from old red blood cells

Bile Production

The liver also produces bile to help digest fats

Nutrient Metabolism

It acts as a powerhouse for activity and helps in the processes the proteins, carbohydrates, and fats for energy

Blood Clotting

It produces proteins necessary for blood coagulation

Blood Volume Regulation

It also maintains proper blood volume in the body

Storage of Energy and Vitamins

The liver also stores glycogen and vitamins for later use

What is the structure of the Liver?

The liver is divided mainly into two parts: a larger right lobe and a smaller left lobe. These lobes contain numerous blood vessels through which blood flows. As blood passes through the liver, toxins and waste products are filtered out and eventually expelled from the body through urine and faeces.

Inside the lobes are thousands of tiny units called lobules. These lobules connect to a network of bile ducts, small tubes that transport bile from the liver to the small intestine, where it aids digestion.

Protecting Your Liver

Since the liver plays so many crucial roles, maintaining its health is vital. Certain diseases, poor diet, excessive alcohol consumption, and other lifestyle factors can damage this organ. Fortunately, a balanced diet, regular exercise, and avoiding harmful substances can go a long way in keeping the liver healthy.


Prabhat Mishra
Prabhat Mishra

Executive - Editorial

    Prabhat Mishra is a Subject Matter Expert and digital journalist with an extensive background in the competitive exam landscape and over 4 years of experience in education, national and international news, and current affairs. Over his tenure with top knowledge platforms like Mentorship India, IAS BABA, IAS SARTHI, and now Jagran Josh, he has a deep understanding of government exams like UPSC and State PCS, including UP and Bihar, as he has already qualified for the UPPCS 2022 Mains and Bihar 68th Mains. With his core expertise in history, polity, geography & current affairs, he specialises in creating well-researched, aspirant-centric content and simplifying complex topics for competitive examinations.

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    First Published: Aug 11, 2025, 16:56 IST

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