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Molecular Basis of Inheritance (Part-1)

A nucleotide has three components – a nitrogenous base, a pentose sugar (ribose in case of RNA, and deoxyribose for DNA), and a phosphate group. Nitrogenous bases are of two types – Purines (Adenine and Guanine), and Pyrimidines (Cytosine, Uracil and Thymine). Cytosine is common for both DNA and RNA and Thymine is present in DNA

Jan 14, 2013 18:22 IST
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Molecular Basis of Inheritance (Part-1)
Molecular Basis of Inheritance (Part-1)

What is Molecular Basis of Inheritance? What is replication? What is autocatalytic formation of DNA? What is semi conservative replication? What is the experimental proof for semi conservative replication? You will get all the answers in this video

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Two nucleotides are linked through 3′-5′ phosphodiester linkage to form a dinucleotide. More nucleotides can be joined in such a manner to form a polynucleotide chain. A polymer thus formed has at one end a free phosphate moiety at 5′-end of ribose sugar, which is referred to as 5’-end of polynucleotide chain. Similarly, at the other end of the polymer the ribose has a free 3′-OH group which is referred to as 3′ – end of the polynucleotide chain.

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